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The Science Notes
  • Cell and Molecular Biology
  • Cancer
  • Bacteriology
  • Biotechnology
  • Facts
  • Immunology
  • Genetics
  • Reproductive Biology
  • Vertebrates
  • Invertebrates
  • Virology
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  • Food Science
  • Vitamins
  • Difference between
  • News & Blogs
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Illustration of Blinatumomab Mechanism
Posted on January 26, 2026 Cancer

Blinatumomab in B-ALL: BiTE Structure, Mechanism, Resistance & Trials

Blinatumomab is a first-in-class BiTE immunotherapy for B-ALL. Explore its molecular structure, T-cell redirection mechanism, resistance pathways, and clinical trials. Read more

Bacterial transformation using Heat shock method
Posted on January 24, 2026 Cell and Molecular Biology

Bacterial Transformation Using the Heat Shock Method

Learn bacterial transformation using the heat shock method with clear steps, principles, applications, and lab relevance. Read more

Serial Dilution and Plating Techniques for Microbial Enumeration and Isolation
Posted on January 20, 2026January 24, 2026 Microbiology

Serial Dilution and Plating Techniques for Microbial Enumeration and Isolation

Learn how serial dilution and plating techniques enable accurate microbial enumeration, isolation, and characterization in laboratory environments. Read more

Posted on January 20, 2026January 20, 2026 Biotechnology Microbiology

Winogradsky Column: Guide to Microbial Communities, Succession, and Biogeochemical Cycles

Comprehensive guide explaining Winogradsky column structure, microbial succession, and biogeochemical cycles in sediment ecosystems. Read more

UV-Vis Spectroscopy Illustration Principles, Instrumentation & Applications
Posted on January 14, 2026 Protocols and Techniques

UV–Visible (UV-Vis) Spectroscopy: Principles, Instrumentation, and Applications

A guide to UV-Vis spectroscopy explaining principles, instrumentation, absorbance, concentration analysis, reaction kinetics, and applications. Read more

Posted on January 14, 2026 Protocols and Techniques

Laboratory Glasswares: Types, Materials, Uses, and Best Practices

A guide to laboratory glassware covering materials, accuracy, connections, cleaning, and common chemistry lab uses. Read more

Illustration explaining Sanger sequencing showing Frederick Sanger, a DNA double helix, fluorescent nucleotides, capillary electrophoresis, and an electropherogram used for DNA sequencing analysis.
Posted on January 14, 2026January 14, 2026 Biotechnology Protocols and Techniques

Sanger Sequencing: Principles, History, Challenges, and Applications

Sanger sequencing explained for students, covering principles, workflow, challenges, and modern applications in DNA sequencing. Read more

Hand-drawn illustration explaining aseptic plating techniques in microbiology, including streak, pour, spread, plaque, and replica plating
Posted on January 13, 2026January 13, 2026 Microbiology

Aseptic Plating Techniques in Microbiology

Learn aseptic plating techniques in microbiology, including streak, pour, spread, plaque assays, and replica plating. Read more

Posted on January 12, 2026January 12, 2026 Cell and Molecular Biology

Hi-C Technology: A Comprehensive Guide to Genome-Wide Chromatin Interactions

Learn Hi-C technology step-by-step to understand 3D genome organization, chromatin interactions, compartments, and fractal globule architecture. Read more

diagram of calibration curves showing standards, linear fit, and LOD/LOQ
Posted on January 11, 2026 Biochemistry Protocols and Techniques

Calibration Curves in Analytical Chemistry: Principles, Procedure, and Applications

Calibration curves are essential tools in analytical chemistry, biochemistry, and pharmaceutical analysis.... Read more

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